December 2020- Monthly Review

Academic Emergency Medicine

Awake Prone Positioning in COVID-19 Hypoxemic Respiratory Failure: Exploratory Findings in a Single-center Retrospective Cohort Study

  • Awake prone positioning was not associated with lower intubation rates. Caution is necessary before widespread adoption of this technique, pending results of clinical trials.

Annals of Emergency Medicine

Obtaining Blood Cultures Before the Administration of Antibiotics and other Emergency Department Fables: An Analysis of the FABLED Study

  • “These data ought not change our current practice of obtaining blood cultures before antibiotic administration. As illness severity increases, the relative importance of early antibiotic administration likely takes precedence over the potential identification of a causative organism. The take-home point for ED clinicians is that timely antibiotic administration should not be delayed because of difficulties in obtaining appropriate samples for blood cultures.”

A Prospective Evaluation of Point-of-Care Ultrasonographic Diagnosis of Diverticulitis in the Emergency Department

  • “Compared with CT, point-of-care ultrasonography had a sensitivity of 92% (95%confidence interval 88% to 96%), specificity of 97% (95% confidence interval 94% to 99%), positive predictive value of 94% (95%confidence interval 90% to 97%), and negative predictive value of 96% (93% to 98%) in the diagnosis of diverticulitis.”
  • Check out the new 5 minute Sono Diverticulitis video later in this post

Are Emergency Practitioners Able to Diagnose Posterior Chamber Abnormalities With Point-of-Care Ocular Ultrasonography?

  • In the studies limited to emergency physicians, ocular point-of-care ultrasonography had a pooled sensitivity of 92% (95% CI 67% to 99%) and specificity of 91%(95% CI 85% to 95%).
  • The authors found emergency practitioner diagnosis of other posterior chamber abnormalities, including lens dislocation, globe rupture, intraocular foreign body, and vit-reous hemorrhage, using point-of-care ultrasonography to be accu-rate, but with wide CIs.
  • The safety of point-of-care ultrasonography for assessment of a ruptured globe or an intraocular foreign body through a penetrating injury has not been established, and using it is not recommended.

Can an Emergency Department–Initiated Intervention Prevent Subsequent Falls and Health Care Use in Older Adults? A Randomized Controlled Trial

  • The two key interventions were pharmacist review of medications and physical therapy consult.
  • Compared with usual care participants (n=55), intervention participants (n=55) were half as likely to experience a subsequent ED visit (adjusted incidence rate ratio 0.47 [95% CI 0.29 to 0.74]) and one third as likely to have fall-related ED visits (adjusted incidence rate ratio 0.34 [95% CI 0.15 to 0.76]) within 6 months.

Critical Care Delivery Solutions in the Emergency Department: Evolving Models in Caring for ICU Boarders

  • An ED length of stay of greater than 6 hours is estimated to be associated with a 10% increase in hospital mortality.
  • A primary determinant (of ICU boarding) is ineffective throughput, reflective of a limited supply of beds, inadequate staffing for the available beds, or ineffective use of beds.
  • 5 models to respond to boarding, easiest is the far right Ed-Base Critical Care Consultation Model.

Missed Opportunities to Diagnose and Intervene in Modifiable Risk Factors for Older Emergency Department Patients Presenting After a Fall

  • In 96% of cases (335/349) in which one or more modifiable risk factors were present, they were not diagnosed. The most commonly missed risk factors were high-risk medications and visual acuity deficits.
  • CDC 12 question checklist
  • Visual acuity
  • Orthostatics
  • Beer’s Medication List
  • Fall Prevention Algorithm
  • Timed Up and Go test- sit in an arm chair, pt has to get up and walk 10 feet in 12 seconds.
  • Test strength at shoulders, elbows, hips, knees.
  • Test sensation in feet to rule out peripheral neuropathy.

Circulation

Randomized Pilot Clinical Trial of Early Coronary Angiography Versus No Early Coronary Angiography After Cardiac Arrest Without ST-Segment Elevation The PEARL Study

  • No mortality benefit to early Cath lab for ROSC patients without STEMI

5 Minute Sono

5 minute Sono Diverticulitis

  • Large curvilinear probe
  • Graded compression up and down
  • Diverticula
  • Bowel wall>5mm
  • Prominent fluid-filled bowel loops
  • Pericolic free fluid
  • Increased pericolic fat (hyperechoic)
  • Abscess

JAMA

Comparison of Acetaminophen (Paracetamol) With Ibuprofen for Treatment of Fever or Pain in Children Younger Than 2 Years A Systematic Review and Meta-analysis

  • Overall, 19 studies (11 randomized; 8 nonrandomized) of 241 138 participants from 7 countries and various health care settings (hospital-based and community-based) were included.
  • In this study, use of ibuprofen vs acetaminophen for the treatment of fever or pain in children younger than 2 years was associated with reduced temperature and less pain within the first 24 hours of treatment, with equivalent safety.

NEJM

Severe Covid-19

Spontaneous Coronary-Artery Dissection

Pathophysiology of Inflammatory Bowel Diseases

Examination of the Neck Veins

Cytokine Storm

Changes in Seizure Frequency and Antiepileptic Therapy during Pregnancy

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