February 2022 Monthly Review

Academic Emergency Medicine

No Feb issue as of March 2, 2022, 2:20pm

American Journal of Emergency Medicine

Dispelling myths and misconceptions about the treatment of acute hyperkalemia

Annals of Emergency Medicine

Rapid Rule-Out of Myocardial Infarction After 30 Minutes as an Alternative to 1 Hour: The RACING-MI Cohort Study

Moving Upstream: A Social Emergency Medicine Approach to Opioid Use Disorder

Man With Eye Pain and Decreased Vision

  • A healthy 39-year-old man presented to the emergency department with 2 days of nontraumatic severe left eye pain and progressive visual loss to the point of blindness. Upon physical examination, the patient reported only flashes of light in the left eye, with sluggish pupillary response and painful extraocular movements. The result of slit lamp examination was unremarkable, and ocular pressures were normal. The result of right eye examination was unremarkable. An emergency physician conducted point-of-care ocular ultrasound, demonstrating evidence of papilledema and optic nerve inflammation 
6.5mm wide optic nerve, ill-defined borders suggest inflammation
Bulge of the optic disc

BMJ

Diagnosis of deep vein thrombosis with D-dimer adjusted to clinical probability: prospective diagnostic management study

  • DVT was considered excluded without further testing by Wells low clinical pretest probability and D-dimer <1000 ng/mL or Wells moderate clinical pretest probability and D-dimer <500 ng/mL. All other patients had proximal ultrasound imaging. Repeat proximal ultrasonography was restricted to patients with initially negative ultrasonography, low or moderate clinical pretest probability, and D-dimer >3000 ng/mL or high clinical pretest probability and D-dimer >1500 ng/mL.
  • Of the 1275 patients with no proximal DVT on scheduled testing who did not receive anticoagulant treatment, eight (0.6%, 95% confidence interval 0.3% to 1.2%) were found to have venous thromboembolism during follow-up. Compared with a traditional DVT testing strategy, this diagnostic approach reduced the need for ultrasonography from a mean of 1.36 scans/patient to 0.72 scans/patient (difference −0.64, 95% confidence interval −0.68 to −0.60), corresponding to a relative reduction of 47%.

Circulation

None

CJEM

Just the facts: how to diagnose and manage patients with multiple myeloma in the emergency department?

EMCRIT

None

Emergency Medicine Journal

Teach-back of discharge instructions in the emergency department: a pre–post pilot evaluation

EMRAP

Devil’s Advocate- Traumatic Arthrotomy

  • Konda SR et al. Computed tomography scan to detect traumatic arthrotomies and identify periarticular wounds not requiring surgical intervention: an improvement over the saline load test. J Orthop Trauma 2013; 27: 498-504.
    • As good as saline load test

Drugs in Atrial Fibrillation with RVR

  • Mag 2-4g IV
  • Dilt 10 as good as .25mg/kg
  • If BP low, give 2g CaGluconate

JAMA

Effect of Noninvasive Respiratory Strategies on Intubation or Mortality
Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19
The RECOVERY-RS Randomized Clinical Trial

  • The requirement for tracheal intubation or mortality within 30 days was significantly lower with CPAP (36.3%; 137 of 377 participants) vs conventional oxygen therapy (44.4%; 158 of 356 participants) (absolute difference, −8% [95% CI, −15% to −1%], P = .03), but was not significantly different with HFNO (44.3%; 184 of 415 participants) vs conventional oxygen therapy (45.1%; 166 of 368 participants) (absolute difference, −1% [95% CI, −8% to 6%], P = .83). 
  • Proning not studied but probably more important than oxygen delivery system

Defining Optimal Respiratory Support for Patients With COVID-19

Journal of Emergency Medicine

None

Lancet

None

NEJM

Stabilizing Health Care’s Share of the GDP

Inherited Patients Taking Opioids for Chronic Pain — Considerations for Primary Care

PEDIATRICS

None

REBELEM

Andexanet Alfa Vs. Four-Factor PCC: Is Andexanet Alfa Worth The Hype?

  • This limited study found no statistically significant difference in stability of oral FXi related ICH after the administration of AA or 4F-PCC. However, the inherent potential bias and small participant numbers limit generalizability and therefore larger prospective studies are needed. 4F-PCC is cheaper and more widely available than AA ($5670/patient, compared to $22,120-$49,500/patient);

Resuscitation

Vasopressin and glucocorticoids for in-hospital cardiac arrest: A systematic review and meta-analysis of individual participant data

  • Improved chance of ROSC but not statistically significant improved hospital discharge.

Leave a comment